Published September 2014 | Version public
Book Section - Chapter

Parallel and Scalable Computation and Spatial Dynamics with DNA-Based Chemical Reaction Networks on a Surface

  • 1. ROR icon California Institute of Technology

Abstract

We propose a theoretical framework that uses a novel DNA strand displacement mechanism to implement abstract chemical reaction networks (CRNs) on the surface of a DNA nanostructure, and show that surface CRNs can perform efficient algorithmic computation and create complex spatial dynamics. We argue that programming molecular behaviors with surface CRNs is systematic, parallel and scalable.

Additional Information

© 2014 Springer International Publishing Switzerland. We thank Ho-Lin Chen and David Yu Zhang for insightful discussions and suggestions. LQ and EW were supported by the Molecular Programming Project under NSF expedition in computing (0832824 and 1317694). LQ was supported by a Career Award at the Scientific Interface from the Burroughs Wellcome Fund (1010684), a Faculty Early Career Development Award from NSF (1351081), and a Okawa Foundation Research Grant (0656180).

Additional details

Identifiers

Eprint ID
79192
Resolver ID
CaltechAUTHORS:20170719-084200345

Funding

NSF
CCF-0832824
NSF
CCF-1317694
Burroughs Wellcome Fund
1010684
NSF
CCF-1351081
Okawa Foundation
0656180

Dates

Created
2017-07-19
Created from EPrint's datestamp field
Updated
2021-11-15
Created from EPrint's last_modified field

Caltech Custom Metadata

Series Name
Lecture Notes in Computer Science
Series Volume or Issue Number
8727