CaltechAUTHORS
Published June 21, 2012 | Version Accepted Version
Journal Article Open

The Brain Activity Map Project and the Challenge of Functional Connectomics

Creators

  • 1. ROR icon University of California, Berkeley
  • 2. ROR icon Kavli Foundation
  • 3. ROR icon Harvard University
  • 4. ROR icon University of California, San Diego
  • 5. ROR icon California Institute of Technology
  • 6. ROR icon Columbia University

Abstract

The function of neural circuits is an emergent property that arises from the coordinated activity of large numbers of neurons. To capture this, we propose launching a large-scale, international public effort, the Brain Activity Map Project, aimed at reconstructing the full record of neural activity across complete neural circuits. This technological challenge could prove to be an invaluable step toward understanding fundamental and pathological brain processes.

Additional Information

© 2012 Elsevier Inc. Available online 20 June 2012. This collaboration arose from a workshop held at Chicheley Hall, the Kavli Royal Society International Centre, supported by The Kavli Foundation, the Gatsby Charitable Foundation, and the Allen Institute for Brain Science. We also thank A.S. Chiang, K. Deisseroth, S. Fraser, C. Koch, E. Marder, O. Painter, H. Park, D. Peterka, S. Seung, A. Siapas, A. Tolias, and X. Zhuang— participants at a smaller, subsequent Kavli Futures Symposium, where initial ideas were jointly refined. We acknowledge support from the DOE (A.P.A.), NHGRI (G.M.C.), NIH and the Mathers Foundation (R.J.G.), NIH and Fondation pour la Recherche et l'Enseignement Superieur, Paris (M.L.R.), and the Keck Foundation and NEI (R.Y.). A more extensive version of this paper and additional documents about the BAM can be found at http://hdl.handle.net/10022/AC:P:13501.

Attached Files

Accepted Version - nihms387480.pdf

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Additional details

Identifiers

PMCID
PMC3597383
Eprint ID
32644
DOI
10.1016/j.neuron.2012.06.006
Resolver ID
CaltechAUTHORS:20120723-113633591

Related works

Describes
10.1016/j.neuron.2012.06.006 (DOI)

Funding

Kavli Foundation
Gatsby Charitable Foundation
Allen Institute for Brain Science
Department of Energy (DOE)
National Human Genome Research Institute (NHGRI)
NIH
Mathers Foundation
Fondation pour la Recherche et l'Enseignement Superieur
Keck Foundation
National Eye Institute

Dates

Created
2012-07-23
Created from EPrint's datestamp field
Updated
2021-11-09
Created from EPrint's last_modified field

Caltech Custom Metadata

Caltech groups
Kavli Nanoscience Institute , Physics Department