Published August 25, 2016
| Version public
Journal Article
Tag Team Ubiquitin Ligases
Creators
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1.
California Institute of Technology
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2.
Howard Hughes Medical Institute
Abstract
Cullin-RING (CRL) and RING1-IBR-RING2 (RBR) are two distinct types of ubiquitin ligases. In this issue, Scott et al. show that CRLs activate the RBR enzyme ARIH1 to initiate ubiquitin chains on CRL substrates, thereby marking an unexpected and important advance in our understanding of both enzymes.
Additional Information
© 2016 Elsevier Inc. R.J.D. is a founder, shareholder, and member of the scientific advisory board of Cleave Biosciences.Additional details
Identifiers
- Eprint ID
- 69980
- DOI
- 10.1016/j.cell.2016.08.014
- Resolver ID
- CaltechAUTHORS:20160829-080930690
Related works
- Describes
- 10.1016/j.cell.2016.08.014 (DOI)
Funding
- Howard Hughes Medical Institute (HHMI)
Dates
- Created
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2016-08-29Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field