Published 1993 | Version Published
Book Section - Chapter Open

Synthesis and Characterization of Periodic Polypeptides Containing Repeating —(AlaGly)_xGluGly— Sequences

Abstract

We have expressed in E. coli a series of periodic polypeptides represented by sequence 1. Our objective has been an understanding of the role of chemical sequence in determining the chain folding behavior of periodic macromolecules. Molecular organization has been examined by infrared spectroscopy and ^1H and ^(13)C NMR methods and a preliminary model of the folded structure has been developed.

Additional Information

© Materials Research Society 1993. This work was supported by a grant from the Polymers and Genetics Programs of the National Science Foundation (DMR-8914359) and by the Materials Research Laboratory at the University of Massachusetts. J. Borbély thanks the Fulbright Foundation for financial support. Dr. Borbély is on leave from the Department of Applied Chemistry, Kossuth Lajos University, H-40 10 Debrecen, Hungary. Yoshikuni Deguchi was on leave from Central Research Laboratories, Kaneka Corporation, 1-2-80, Yoshida-cho, Hyogo-ku, Kobe 652, JAPAN.

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Eprint ID
54569
Resolver ID
CaltechAUTHORS:20150209-130326443

Funding

NSF
DMR-8914359
Fulbright Foundation

Dates

Created
2015-03-07
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Updated
2021-11-10
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Series Name
Materials Research Society Symposia Proceedings
Series Volume or Issue Number
292