Published December 3, 2022
| Version Submitted
Discussion Paper
Open
Annotation-agnostic discovery of associations between novel gene isoforms and phenotypes
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1.
California Institute of Technology
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2.
University of Iceland
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3.
deCODE Genetics (Iceland)
Abstract
We present a novel method for associating phenotypes with RNA expression, that can identify expression associations resulting from a wide variety of underlying transcriptional and post-transcriptional events, without relying on annotations of these events. We show that we can reliably detect,de novo, phenotypically relevant transcriptional structures
Additional Information
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license. The authors have declared no competing interest.Attached Files
Submitted - 2022.12.02.518787v1.full.pdf
Files
2022.12.02.518787v1.full.pdf
Additional details
Identifiers
- Eprint ID
- 120171
- Resolver ID
- CaltechAUTHORS:20230316-182788000.61
Dates
- Created
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2023-03-17Created from EPrint's datestamp field
- Updated
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2023-03-17Created from EPrint's last_modified field
Caltech Custom Metadata
- Caltech groups
- Division of Biology and Biological Engineering (BBE)