The Acetylation of Some Substituted Ferrocenes

A number of mono- and disubstituted ferrocenes have been acetylated. It has been found that iodine is lost from iodoferrocene under the acetylation conditions employed. Contrary to another report, bromo- and chloroferrocenes are acetylated to give 1'-acetylbromo- and chloroferrocenes in good yield. Acetylation of acetamido- and urethanoferrocenes gives predominantly the heteroannulsrly substituted isomers, and these substituents are deactivating.