CaltechAUTHORS
Published April 2020 | Version public
Journal Article Metadata-only

Human sperm RNA code senses dietary sugar

Creators

  • 1. ROR icon Institute of Zoology
  • 2. ROR icon California Institute of Technology
  • 3. ROR icon University of California, Riverside

Abstract

A new study reveals that a high-sugar diet acutely alters human sperm small RNA profiles after 1 week and that these changes are associated with changes in sperm motility. This rapid response by sperm to nutritional fluctuation raises intriguing questions regarding the underlying mechanisms and the potential effects on offspring metabolic health.

Additional Information

© 2020 Springer Nature Limited. Published 17 February 2020; Issue Date: April 2020. The authors thank Xudong Zhang for discussion. Y.Z. is supported by MOST (2019YFA0802600 and 2018YFC1004500) and Q.C. is supported by NIH (R01HD092431). The authors declare no competing interests.

Additional details

Identifiers

PMCID
PMC7080589
Eprint ID
101316
DOI
10.1038/s41574-020-0331-2
Resolver ID
CaltechAUTHORS:20200218-080734483

Related works

Describes
10.1038/s41574-020-0331-2 (DOI)

Funding

Ministry of Science and Technology (Taipei)
2019YFA0802600
Ministry of Science and Technology (Taipei)
2018YFC1004500
NIH
R01HD092431

Dates

Created
2020-02-18
Created from EPrint's datestamp field
Updated
2021-11-16
Created from EPrint's last_modified field