CaltechAUTHORS
Published March 16, 2009 | Version Accepted Version
Journal Article Open

Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers

Creators

  • 1. ROR icon Texas A&M University
  • 2. ROR icon Mayo Clinic
  • 3. ROR icon Washington University in St. Louis

Abstract

In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with "side viewing" capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.

Additional Information

© 2008 Elsevier B.V. Received 6 May 2008; Received in revised form 25 October 2008; Accepted 7 November 2008; Available online 25 November 2008. This project is partially supported by National Institutes of Health under contract R01 CA106728.

Attached Files

Accepted Version - nihms117654.pdf

Files

nihms117654.pdf

Files (3.2 MB)

Name Size
md5:774f2383773fa11e0261dee84412241f
3.2 MB Preview Download

Additional details

Identifiers

PMCID
PMC4286192
Eprint ID
70492
DOI
10.1016/j.sna.2008.11.008
Resolver ID
CaltechAUTHORS:20160921-092710571

Related works

Describes
10.1016/j.sna.2008.11.008 (DOI)

Funding

NIH
R01 CA106728

Dates

Created
2016-09-29
Created from EPrint's datestamp field
Updated
2021-11-11
Created from EPrint's last_modified field