Published June 15, 2012
| Version Supplemental Material
Journal Article
Open
Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids
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1.
Ewha Womans University
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2.
California Institute of Technology
Abstract
A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good yields. This systematic solid-phase CM study can provide facile access to the molecular sources of glycopeptidomimetics and postchemical modifications on various molecular scaffolds.
Additional Information
© 2012 American Chemical Society. Received April 2, 2012. Publication Date (Web): June 7, 2012. This research was supported by the World Class University (WCU) program (R33-10169) and the Basic Science Research Program (2009-0068960) through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology. This work was also supported by the Ewha Global Top 5 Grant 2011 of Ewha Womans University.Attached Files
Supplemental Material - ol300808c_si_001.pdf
Files
ol300808c_si_001.pdf
Additional details
Identifiers
- Eprint ID
- 32331
- DOI
- 10.1021/ol300808c
- Resolver ID
- CaltechAUTHORS:20120710-131446965
Related works
- Describes
- 10.1021/ol300808c (DOI)
Funding
- World Class University (WCU)
- R33-10169
- National Research Foundation of Korea
- 2009-0068960
- Ewha Womans University
Dates
- Created
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2012-07-12Created from EPrint's datestamp field
- Updated
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2021-11-09Created from EPrint's last_modified field