CaltechAUTHORS
Published November 18, 2011 | Version Accepted Version
Journal Article Open

Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor

Creators

  • 1. ROR icon University of Freiburg
  • 2. ROR icon California Institute of Technology

Abstract

The identity of the interstitial light atom in the center of the FeMo cofactor of nitrogenase has been enigmatic since its discovery. Atomic-resolution x-ray diffraction data and an electron spin echo envelope modulation (ESEEM) analysis now provide direct evidence that the ligand is a carbon species.

Additional Information

© 2011 American Association for the Advancement of Science. Received 15 September 2011; accepted 19 October 2011. We thank the staff at Swiss Light Source, Villigen, Switzerland, and S. M. Consiglio for assistance with the calculations. The work was supported by Deutsche Forschungsgemeinschaft (grants Ei-520/7 to O.E., An-676/1 to S.L.A.A., and IRTG 1478), Natural Sciences and Engineering Research Council of Canada postdoctoral fellowship to L.Z., NIH (grant GM45162 to D.C.R.), and HHMI (to D.C.R.). The structural model and structure factors have been deposited with the Protein Data Bank (accession code 3U7Q).

Attached Files

Accepted Version - nihms349905.pdf

Files

nihms349905.pdf

Files (166.7 kB)

Name Size
md5:597ac51d5e15ab593266b0712ba4e2e4
166.7 kB Preview Download

Additional details

Identifiers

PMCID
PMC3268367
Eprint ID
28340
Resolver ID
CaltechAUTHORS:20111207-101914652

Funding

Deutsche Forschungsgemeinschaft (DFG)
Ei-520/7
Deutsche Forschungsgemeinschaft (DFG)
An-676/1
Deutsche Forschungsgemeinschaft (DFG)
IRTG 1478
Natural Sciences and Engineering Research Council of Canada (NSERC)
NIH
GM45162
Howard Hughes Medical Institute (HHMI)

Dates

Created
2011-12-07
Created from EPrint's datestamp field
Updated
2021-11-09
Created from EPrint's last_modified field

Caltech Custom Metadata

Other Numbering System Name
Protein Bank accession code
Other Numbering System Identifier
3U7Q