CaltechAUTHORS
Published January 2021 | Version public
Journal Article Metadata-only

NIH Workshop 2018: Towards Minimally Invasive or Noninvasive Approaches to Assess Tissue Oxygenation Pre- and Post-transfusion

Creators

  • 1. ROR icon National Heart Lung and Blood Institute
  • 2. ROR icon Columbia University
  • 3. ROR icon Eastern Virginia Medical School
  • 4. ROR icon Stony Brook University
  • 5. ROR icon University of Alabama at Birmingham
  • 6. ROR icon Center for Cancer Research
  • 7. ROR icon University of Maryland, Baltimore
  • 8. ROR icon Massachusetts General Hospital
  • 9. ROR icon Harvard University
  • 10. ROR icon Arizona State University
  • 11. ROR icon Catalyst Biosciences (United States)
  • 12. ROR icon California Institute of Technology
  • 13. ROR icon Children's National Health System
  • 14. ROR icon New York Blood Center
  • 15. ROR icon Emory University
  • 16. ROR icon Mayo Clinic
  • 17. ROR icon University of Pennsylvania
  • 18. ROR icon Profusa (United States)

Abstract

Because blood transfusion is one of the most common therapeutic interventions in hospitalized patients, much recent research has focused on improving the storage quality in vitro of donor red blood cells (RBCs) that are then used for transfusion. However, there is a significant need for enhancing our understanding of the efficacy of the transfused RBCs in vivo. To this end, the NIH sponsored a one-and-a-half-day workshop that brought together experts in multiple disciplines relevant to tissue oxygenation (eg, transfusion medicine, critical care medicine, cardiology, neurology, neonatology and pediatrics, bioengineering, biochemistry, and imaging). These individuals presented their latest findings, discussed key challenges, and aimed to identify opportunities for facilitating development of new technologies and/or biomarker panels to assess tissue oxygenation in a minimally-invasive to non-invasive fashion, before and after RBC transfusion.

Additional Information

© 2020 Elsevier. Available online 6 December 2020. More information about the NIH Workshop can be found at: https://www.nhlbi.nih.gov/events/2018/tissue-oxygenation-workshop. The authors would like to thank James Berger and Richard Henry from the Office of the Assistant Secretary for Health, DHHS for their contribution to the workshop design. Author Contributions: All authors participated in the meeting, contributed talks, and prepared the initial drafts of the sections identified with them. Drs. Ochocinska, Glynn, and Spitalnik compiled and edited the texts, wrote the initial drafts of the Introduction and Conclusions, and organized the overall manuscript. All authors read and approved the final draft. Role of the Funding Source: This costs of organizing the meeting and travel reimbursement for the invited speakers were provided by the National Heart, Lung, and Blood Institute. Otherwise, the authors have no competing interests to declare. Declaration of Interest: This costs of organizing the meeting and travel reimbursement for the invited speakers were provided by the National Heart, Lung, and Blood Institute. Nonetheless, the summaries contributed by each author represent their own opinions. Otherwise, the authors have no competing interests to declare.

Additional details

Identifiers

Eprint ID
106965
DOI
10.1016/j.tmrv.2020.12.003
Resolver ID
CaltechAUTHORS:20201208-105038694

Related works

Describes
10.1016/j.tmrv.2020.12.003 (DOI)
https://www.nhlbi.nih.gov/events/2018/tissue-oxygenation-workshop (URL)

Funding

NIH

Dates

Created
2020-12-09
Created from EPrint's datestamp field
Updated
2021-11-16
Created from EPrint's last_modified field