CaltechAUTHORS
Published April 4, 2014 | Version Published
Patent Open

Imidazo bibyclic imminium compounds as antitumor agents

Creators

Abstract

The invention relates to imidazobicycles having a quaternary nitrogen that are inhibitors of the Hedgehog pathway and therefore useful as antitumor agents and as probes of the function of Hedgehog-dependent systems.

Additional Information

Appl. No.: 14/409,683 Filed: June 19, 2013 PCT Filed: June 19, 2013 PCT No.: PCT/US2013/046560 371(c)(1),(2),(4) Date: December 19, 2014 PCT Pub. No.: WO2013/192301 PCT Pub. Date: December 27, 2013. Government Interests: This invention was made with Government support under contract CA136574 awarded by the National Institutes of Health. The Government has certain rights in this invention. Parent Case Text: This application is a national phase filing under 35 U.S.C. .sctn.371 of PCT International Application PCT/US2013/046560, filed Jun. 19, 2013, and published under PCT Article 21(2) as WO 2013/192301 on Dec. 27, 2013. PCT/US2013/046560 claims priority from U.S. provisional application 61/662,977, filed Jun. 22, 2012. The contents of each of the prior applications are incorporated herein by reference in their entirety.

Attached Files

Published - EP2864332B1.pdf

Published - US9611276B2.pdf

Files

EP2864332B1.pdf

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Additional details

Identifiers

Eprint ID
81083
Resolver ID
CaltechAUTHORS:20170901-135026964

Related works

Describes
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=%22US+9611276%22&OS= (URL)
https://www.google.com/patents/US9611276 (URL)
https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161228&DB=&locale=en_EP&CC=EP&NR=2864332B1&KC=B1&ND=5 (URL)
https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131227&DB=&locale=en_EP&CC=WO&NR=2013192301A1&KC=A1&ND=7 (URL)

Funding

NIH
CA136574

Dates

Created
2017-09-21
Created from EPrint's datestamp field
Updated
2022-04-25
Created from EPrint's last_modified field