CaltechAUTHORS
Published September 1999 | Version public
Journal Article Metadata-only

Recognition and Reaction of Metallointercalators with DNA

Creators

  • 1. ROR icon California Institute of Technology

Abstract

The design of small complexes that bind and react at specific sequences of DNA becomes important as we begin to delineate, on a molecular level, how genetic information is expressed. A more complete understanding of how to target DNA sites with specificity will lead not only to novel chemotherapeutics but also to a greatly expanded ability for chemists to probe DNA and to develop highly sensitive diagnostic agents.

Additional Information

© 1999 American Chemical Society. Received May 17, 1999 Revised Manuscript Received July 5, 1999. Publication Date (Web): August 3, 1999. We are grateful to the NIH (GM33309) for their financial support. We also thank our many coworkers and collaborators, as cited, as well as the many researchers from other laboratories who helped elucidate the chemistry of metallointercalators.

Additional details

Identifiers

Eprint ID
65993
DOI
10.1021/cr9804341
Resolver ID
CaltechAUTHORS:20160407-115524676

Related works

Describes
10.1021/cr9804341 (DOI)

Funding

NIH
GM33309

Dates

Created
2016-04-11
Created from EPrint's datestamp field
Updated
2021-11-10
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