CaltechAUTHORS
Published March 3, 2003 | Version public
Journal Article Metadata-only

Molecular Mousetraps: Gas-Phase Studies of the Covalent Coupling of Noncovalent Complexes Initiated by Reactive Carbenes Formed by Controlled Activation of Diazo Precursors

Creators

  • 1. ROR icon California Institute of Technology

Abstract

The covalent linking of noncovalently bound host–guest complexes in the gas phase is achieved by the formation of a highly reactive carbene from the host molecule, which is generated by collision-activated dissociation. Possible mechanisms for the resulting intermolecular reactions are explored by theory and experiment.

Additional Information

© 2003 John Wiley & Sons. Received: October 23, 2002. The authors gratefully acknowledge funding provided by NSF (Grant CHE-9727566), the Beckman Institute Foundation, the California Institute of Technology, the Camille and Henry Dreyfus Foundation (New Faculty Award to B.M.S.), and Abbott Labs (graduate fellowship to J.A.M.). Special thanks to the Peter Dervan group for aid in the use of their HPLC apparatus.

Additional details

Identifiers

Eprint ID
74515
DOI
10.1002/anie.200390258
Resolver ID
CaltechAUTHORS:20170223-161950902

Funding

NSF
CHE-9727566
Arnold and Mabel Beckman Foundation
Caltech Beckman Institute
Camille and Henry Dreyfus Foundation
Abbott Laboratories

Dates

Created
2017-02-24
Created from EPrint's datestamp field
Updated
2021-11-11
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