Published April 26, 2023 | Version In Press
Journal Article Open

Spatial tropism profiling of AAV vectors by ultrasensitive sequential FISH in tissue

Abstract

Ultrasensitive sequential fluorescence in situ hybridization (USeqFISH) enables multiplexed detection of the expression of endogenous and exogenous genes delivered by adeno-associated virus (AAV) vectors in intact tissue. USeqFISH provides a spatial map of AAV tropism with high throughput and resolution.

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© 2023 Nature Publishing Group.

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PMCID
PMC9885914
Eprint ID
119437
Resolver ID
CaltechAUTHORS:20230221-20005500.75

Dates

Created
2023-04-26
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Updated
2023-04-26
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