CaltechAUTHORS
Published January 4, 2016 | Version Published
Journal Article Open

WormBase 2016: expanding to enable helminth genomic research

Creators

  • 1. ROR icon European Bioinformatics Institute
  • 2. ROR icon Ontario Institute for Cancer Research
  • 3. ROR icon California Institute of Technology
  • 4. ROR icon Wellcome Sanger Institute
  • 5. ROR icon Washington University in St. Louis

Abstract

WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved from its original remit to collect and integrate all data for a single species, and now extends to numerous nematodes, ranging from evolutionary comparators of C. elegans to parasitic species that threaten plant, animal and human health. Research activity using C. elegans as a model system is as vibrant as ever, and we have created new tools for community curation in response to the ever-increasing volume and complexity of data. To better allow users to navigate their way through these data, we have made a number of improvements to our main website, including new tools for browsing genomic features and ontology annotations. Finally, we have developed a new portal for parasitic worm genomes. WormBase ParaSite (parasite.wormbase.org) contains all publicly available nematode and platyhelminth annotated genome sequences, and is designed specifically to support helminth genomic research.

Additional Information

© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Received September 30, 2015; Revised October 26, 2015; Accepted October 28, 2015. Nucleic Acids Research Advance Access published November 17, 2015. After many years working closely with WormBase as the guardian and authority for C. elegans genetic nomenclature, Jonathan Hodgkin has now stepped down from this role. We would like to thank him for his guidance and leadership. US National Human Genome Research Institute [U41-HG002223]; UK Medical Research Council [MR/L001220]; UK Biotechnology and Biological Sciences Research Council [BB/K020080 to WormBase]; P.W.S. is an investigator with the Howard Hughes Medical Institute. Funding for open access charge: US National Human Genome Research Institute [U41-HG002223]. Conflict of interest statement. None declared.

Attached Files

Published - Nucl._Acids_Res.-2016-Howe-D774-80.pdf

Files

Nucl._Acids_Res.-2016-Howe-D774-80.pdf

Files (3.1 MB)

Name Size
md5:116e1448c57ff2e461c64c367f507683
3.1 MB Preview Download

Additional details

Identifiers

PMCID
PMC4702863
Eprint ID
62374
Resolver ID
CaltechAUTHORS:20151124-111442659

Related works

Describes
http://www.wormbase.org/ (URL)
http://parasite.wormbase.org (URL)

Funding

NIH
U41-HG002223
Medical Research Council (MRC)
MR/L00122
Biotechnology and Biological Sciences Research Council (BBSRC)
BB/K020080
Howard Hughes Medical Institute (HHMI)
National Human Genome Research Institute

Dates

Created
2015-11-24
Created from EPrint's datestamp field
Updated
2022-05-13
Created from EPrint's last_modified field