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Published February 11, 2013 | Version Supplemental Material
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Diastereoselective Povarov-Like Reaction Involving O-Pivaloylated D-Galactosylimine

Creators

  • 1. ROR icon Peking University
  • 2. ROR icon California Institute of Technology

Abstract

A diastereoselective Povarov-like reaction using O-pivaloylated β-D-galactosylamine as the chiral auxiliary is described. The three-component reaction of chiral aldimines, cyclic enol ethers and nucleophiles afforded the desired products in good yields and high content of the main isomer. This procedure provides an efficient method to obtain multifunctional molecules carrying three contiguous chiral centers in high stereoselectivity.

Additional Information

© 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: August 24, 2012; Published online: January 9, 2013. This work was supported by grants from the National Natural Science Foundation of China (NSFC) (No. 21072017, 20732001).

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Additional details

Identifiers

Eprint ID
75533
DOI
10.1002/adsc.201200761
Resolver ID
CaltechAUTHORS:20170330-073929213

Funding

National Natural Science Foundation of China
21072017
National Natural Science Foundation of China
20732001

Dates

Created
2017-03-30
Created from EPrint's datestamp field
Updated
2021-11-15
Created from EPrint's last_modified field