Published April 1996 | Version public
Journal Article

Extending the recognition site of designed minor groove binding molecules

  • 1. ROR icon University of California, Berkeley
  • 2. ROR icon California Institute of Technology

Abstract

A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode.

Additional Information

© 1996 Nature Publishing Group. Received 28 August 1995; Accepted 22 February 1996. B.H.G. and D.E.W. thank H.P. Spielmann, P.A. Fagan, T.D. Cole and R. Pelaez for helpful discussions. We are grateful to National Institutes of Health and the National Foundation for Cancer Research for research support, to the Ralph M. Parson Foundation for a graduate fellowship to M.M., and to the U.S. Department of Energy and National Science Foundation for instrumentation grants.

Additional details

Identifiers

Eprint ID
58590
DOI
10.1038/nsb0496-321
Resolver ID
CaltechAUTHORS:20150624-144700360

Related works

Describes
10.1038/nsb0496-321 (DOI)

Funding

NIH
National Foundation for Cancer Research
Ralph M. Parsons Foundation
Department of Energy (DOE)
NSF

Dates

Created
2015-06-24
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Updated
2021-11-10
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