New methods and strategies for the enantioselective synthesis of polycyclic natural products

The overarching goal of the Reisman lab. is to discover, develop, and study new chem. reactions within the context of natural product total synthesis. The chem. synthesis of natural products enables the study of their biol. mechanisms, and can provide access to synthetic derivs. with improved therapeutic properties. As importantly, these synthetic undertakings serve to drive innovation in, and deepen our fundamental understanding of, org. and organometallic chem. This seminar will describe our latest progress in both our methodol. and target-directed synthesis endeavors.