Published June 16, 2017 | Version public
Journal Article

Response to Comment on "Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing"

  • 1. ROR icon California Institute of Technology

Abstract

Wang et al. question whether Lamin B receptor is required for Xist-mediated silencing because they claim that our cells contain an inversion rather than a deletion. We present evidence that these cells contain a proper deletion and that the confusion is caused by DNA probes used in the experiment. Accordingly, the points raised have no effect on the conclusions in our paper.

Additional Information

© 2017 American Association for the Advancement of Science. Received 1 February 2017; accepted 8 May 2017.

Additional details

Identifiers

Eprint ID
78263
Resolver ID
CaltechAUTHORS:20170616-092953242

Dates

Created
2017-06-16
Created from EPrint's datestamp field
Updated
2021-11-15
Created from EPrint's last_modified field