CaltechAUTHORS
Published December 2023 | Version Published
Journal Article Open

Cephalopod-omics: Emerging Fields and Technologies in Cephalopod Biology

Creators

  • 1. ROR icon University of Sussex
  • 2. ROR icon University of Connecticut
  • 3. ROR icon University of Oregon
  • 4. ROR icon MRC Laboratory of Molecular Biology
  • 5. ROR icon University of Washington
  • 6. ROR icon Johns Hopkins University
  • 7. ROR icon Stazione Zoologica Anton Dohrn
  • 8. ROR icon Instituto de Investigaciones Marinas
  • 9. ROR icon University of Central Florida
  • 10. ROR icon Michigan State University
  • 11. ROR icon University of Adelaide
  • 12. ROR icon University of Tokyo
  • 13. ROR icon Adam Mickiewicz University in Poznań
  • 14. ROR icon Okinawa Institute of Science and Technology
  • 15. ROR icon University of Vienna
  • 16. ROR icon New York University Abu Dhabi
  • 17. ROR icon Stanford University
  • 18. ROR icon University of California, Merced
  • 19. ROR icon University of Lisbon
  • 20. ROR icon Carnegie Institution for Science
  • 21. ROR icon Marine Biological Laboratory
  • 22. ROR icon University of Hawaii at Manoa
  • 23. ROR icon KU Leuven
  • 24. ROR icon Helmholtz Association of German Research Centres
  • 25. ROR icon Ocean University of China
  • 26. ROR icon University of Chicago

Abstract

Synopsis Few animal groups can claim the level of wonder that cephalopods instill in the minds of researchers and the general public. Much of cephalopod biology, however, remains unexplored: the largest invertebrate brain, difficult husbandry conditions, and complex (meta-)genomes, among many other things, have hindered progress in addressing key questions. However, recent technological advancements in sequencing, imaging, and genetic manipulation have opened new avenues for exploring the biology of these extraordinary animals. The cephalopod molecular biology community is thus experiencing a large influx of researchers, emerging from different fields, accelerating the pace of research in this clade. In the first post-pandemic event at the Cephalopod International Advisory Council (CIAC) conference in April 2022, over 40 participants from all over the world met and discussed key challenges and perspectives for current cephalopod molecular biology and evolution. Our particular focus was on the fields of comparative and regulatory genomics, gene manipulation, single-cell transcriptomics, metagenomics, and microbial interactions. This article is a result of this joint effort, summarizing the latest insights from these emerging fields, their bottlenecks, and potential solutions. The article highlights the interdisciplinary nature of the cephalopod-omics community and provides an emphasis on continuous consolidation of efforts and collaboration in this rapidly evolving field.

Copyright and License

© The Author(s) 2023. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

Conflict of Interest

The authors declare that there is no conflict of interest.

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Additional details

Identifiers

ISSN
1557-7023
PMCID
PMC10755191