Published June 2011 | Version public
Journal Article

Turing's next steps: the mechanochemical basis of morphogenesis

  • 1. ROR icon Max Planck Institute of Molecular Cell Biology and Genetics
  • 2. ROR icon Max Planck Institute for the Physics of Complex Systems
  • 3. ROR icon University of California, Los Angeles

Abstract

Nearly 60 years ago, Alan Turing showed theoretically how two chemical species, termed morphogens, diffusing and reacting with each other can generate spatial patterns. Diffusion plays a crucial part in transporting chemical signals through space to establish the length scale of the pattern. When coupled to chemical reactions, mechanical processes — forces and flows generated by motor proteins — can also define length scales and provide a mechanochemical basis for morphogenesis. forces and flows generated by motor proteins — can also define length scales and provide a mechanochemical basis for morphogenesis.

Additional Information

© 2011 Macmillan Publishers Limited. Published 23 May 2011; Issue Date June 2011. We thank N. Goehring, M. Mayer and F. Jülicher for discussions, and I. Tolic-Norrelykke for comments on the manuscript. The authors declare no competing financial interests.

Additional details

Identifiers

Eprint ID
102496
DOI
10.1038/nrm3120
Resolver ID
CaltechAUTHORS:20200413-090213788

Related works

Describes
10.1038/nrm3120 (DOI)

Dates

Created
2020-04-13
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Updated
2021-11-16
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