Published January 1991 | Version public
Journal Article

The major serum protein of Drosophila larvae, larval serum protein 1, is dispensable

  • 1. ROR icon University of Oxford
  • 2. ROR icon Newcastle University
  • 3. ROR icon Imperial College London

Abstract

Null alleles of all three genes (α, β and γ) coding for the major serum protein of Drosophila larvae, larval serum protein 1, have been characterized at the protein level and by analysis of their RNA and DNA. Each allele completely lacks one polypeptide chain. β° shows an unaltered gene but reduced levels of RNA, α° shows restriction‐fragment‐length polymorphism and shows low levels of transcript, while γ° is a deletion. The three null alleles have been combined to give a strain without the gene for larval serum protein 1 which survives

Additional Information

© FEBS 1991. (Received August 23, 1990) We would like to acknowledge, once again, our debt of gratitude to Jean Matthews for feeding the flies. The work was supported by a grant from the Science and Engineering Research Council to DBR and a grant from the Clinical Research Council to DS and DG.

Additional details

Identifiers

Eprint ID
106032
DOI
10.1111/j.1432-1033.1991.tb15695.x
Resolver ID
CaltechAUTHORS:20201013-133531975

Related works

Funding

Science and Engineering Research Council (SERC)
Clinical Research Council

Dates

Created
2020-10-13
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Updated
2021-11-16
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