Published August 15, 1968
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A Proton Magnetic Resonance Study of The Interaction of Adenosine with Polyuridylic Acid: Evidence for Both Adenine-Uracil Base-Stacking and Base-Pairing
Creators
Abstract
We report here a proton magnetic resonance (pmr) study of the interaction of adenosine with polyuridylic acid in aqueous solution. The results of this study indicate that the mode of interaction is adenosine intercalation and adenine-uracil base-stacking above 26[degrees]C, and verifies that a triple-stranded complex which is stabilized by both adenine-uracil hydrogen-bonding and adenine-adenine base-stacking is formed below this temperature. Some information regarding the dynamics of these processes has also been obtained.
Additional Information
© 1968 by the National Academy of Sciences Communicated by Norman Davidson, May 15, 1968 This work was supported in part by grant GM-14523-02, U.S. Public Health Service. Noyes Laboratory of Chemical Physics, Contribution no. 3676.Attached Files
Published - BANpnas68.pdf
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BANpnas68.pdf
Additional details
Identifiers
- PMCID
- PMC224893
- Eprint ID
- 723
- Resolver ID
- CaltechAUTHORS:BANpnas68
Related works
- Describes
- http://www.pnas.org/cgi/reprint/60/4/1144 (URL)
Funding
- NIH
- GM-14523-02
Dates
- Created
-
2005-09-20Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field
Caltech Custom Metadata
- Other Numbering System Name
- Arthur Amos Noyes Laboratory of Chemical Physics
- Other Numbering System Identifier
- 3676