CaltechAUTHORS
Published November 2019 | Version public
Journal Article Metadata-only

A 512-Pixel, 51-kHz-Frame-Rate, Dual-Shank, Lens-Less, Filter-Less Single-Photon Avalanche Diode CMOS Neural Imaging Probe

Creators

  • 1. ROR icon Columbia University
  • 2. ROR icon Korea Institute of Science and Technology
  • 3. ROR icon Electronics and Telecommunications Research Institute
  • 4. ROR icon California Institute of Technology

Abstract

We present an implantable single-photon shank-based imager, monolithically integrated onto a single CMOS IC. The imager comprises of 512 single-photon avalanche diodes distributed along two shanks, with a 6-bit depth in-pixel memory and an on-chip digital-to-time converter. To scale down the system to a minimally invasive form factor, we substitute optical filtering and focusing elements with a time-gated, angle-sensitive detection system. The imager computationally reconstructs the position of fluorescent sources within a 3-D volume of 3.4 mm × 600 μm× 400 μm .

Additional Information

© 2019 IEEE. Manuscript received May 14, 2019; revised August 1, 2019; accepted August 28, 2019. Date of current version October 23, 2019. This article was approved by Associate Editor Pedram Mohseni. This work was supported in part by the National Institutes of Health under Grant U01NS090596, in part by the Defense Advanced Research Projects Agency (DARPA) under Contract N66001–17-C-4012, and in part by the U.S. Army Research Laboratory and the U.S. Army Research Office under Contract W911NF-12–1-0594.

Additional details

Identifiers

Eprint ID
99588
Resolver ID
CaltechAUTHORS:20191031-124926910

Funding

NIH
U01NS090596
Defense Advanced Research Projects Agency (DARPA)
N66001-17-C-4012
Army Research Laboratory
Army Research Office (ARO)
W911NF-12-1-0594

Dates

Created
2019-10-31
Created from EPrint's datestamp field
Updated
2021-11-16
Created from EPrint's last_modified field

Caltech Custom Metadata

Caltech groups
Physics Department