Published July 2017 | Version Accepted Version
Journal Article Open

OPA1 and cardiolipin team up for mitochondrial fusion

  • 1. ROR icon California Institute of Technology

Abstract

Fusion between the inner membranes of two mitochondria requires the GTPase optic atrophy 1 (OPA1), but the molecular mechanism is poorly understood. A study now shows that fusion of two liposomes can be performed by OPA1 tethered to just one liposome, through an interaction with the phospholipid cardiolipin on the opposing liposome.

Additional Information

© 2017 Macmillan Publishers Limited, part of Springer Nature. Published online 19 June 2017. The authors declare no competing financial interests.

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Identifiers

PMCID
PMC5757513
Eprint ID
78366
Resolver ID
CaltechAUTHORS:20170620-091459936

Dates

Created
2017-06-20
Created from EPrint's datestamp field
Updated
2022-03-25
Created from EPrint's last_modified field