Published June 2022
| Version Accepted Version
Journal Article
Open
Forced entry into the nucleus
Abstract
The nuclear pore complex (NPC) regulates transport of macromolecules into and out of the nucleus. A study now shows that mechanical force applied on the nucleus affects the transport rates across the NPC diffusion barrier, modulating the nuclear localization of certain cargos.
Additional Information
© 2022 Nature Publishing Group. Published 09 June 2022. The authors declare no competing interests.Attached Files
Accepted Version - nihms-1824469.pdf
Files
nihms-1824469.pdf
Additional details
Identifiers
- PMCID
- PMC9348904
- Eprint ID
- 115167
- Resolver ID
- CaltechAUTHORS:20220615-392838600
Funding
- Howard Hughes Medical Institute (HHMI)
- 55108534
- NIH
- GM117360
- NIH
- GM111461
Dates
- Created
-
2022-06-17Created from EPrint's datestamp field
- Updated
-
2022-08-16Created from EPrint's last_modified field