Field-based multiplex and quantitative assay platforms for diagnostics
Creators
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1.
Intelligent Optical Systems (United States)
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2.
University of Pittsburgh
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3.
University of Arizona
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4.
California Institute of Technology
Contributors
Abstract
The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.
Additional Information
© 2011 SPIE. This work was funded by support from an Army SBIR contract (Contract # W81XWH07-C-0031) and an Air Force SBIR Contract (FA8650-07-C-6757). The author is indebted to project technical monitors Dr. Madhusoodana Nambiar and Dr. Camilla Mauzy for their suggestions and support in the development of this work.Attached Files
Published - 80290P_1.pdf
Files
80290P_1.pdf
Additional details
Identifiers
- Eprint ID
- 71585
- Resolver ID
- CaltechAUTHORS:20161028-140214165
Funding
- Army Research Office (ARO)
- W81XWH07-C-0031
- Air Force Office of Scientific Research (AFOSR)
- FA8650-07-C-6757
Dates
- Created
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2016-10-31Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field
Caltech Custom Metadata
- Caltech groups
- Physics Department
- Series Name
- Proceedings of SPIE
- Series Volume or Issue Number
- 8029