Published March 26, 2012 | Version Published
Journal Article Open

Slow light for deep tissue imaging with ultrasound modulation

  • 1. ROR icon Texas A&M University
  • 2. ROR icon Lund University
  • 3. ROR icon Washington University in St. Louis

Abstract

Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scatteringtissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm^(−1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection.

Additional Information

© 2012 American Institute of Physics. Received 6 February 2012; accepted 5 March 2012; published online 26 March 2012. S.K. was sponsored in part by the Swedish Research Council, the Knut & Alice Wallenberg Foundation, the Crafoord Foundation and the EC FP7 Contract No. 247743 (QuRep). L.V.W. was sponsored in part by National Institutes of Health grants R01 EB000712 and U54 CA136398.

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Additional details

Identifiers

PMCID
PMC3326061
Eprint ID
68782
Resolver ID
CaltechAUTHORS:20160630-102054201

Funding

Swedish Research Council
Knut and Alice Wallenberg Foundation
Crafoord Foundation
European Commission
247743
NIH
R01 EB000712
NIH
U54 CA136398

Dates

Created
2016-07-06
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Updated
2021-11-11
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