CaltechAUTHORS
Published September 1, 1977 | Version public
Journal Article Metadata-only

The protonation site of vitamin B_1 as determined from natural-abundance nitrogen-15 nuclear magnetic resonance spectra

Creators

Abstract

Natural-abundance nitrogen-15 nuclear magnetic resonance spectroscopy has been used to determine the site of protonation in vitamin B_1. Selectively decoupling individual protons of the vitamin in water, D_2O, and ethylene glycol permitted assignment of the nitrogen resonances and thence the determination of the site of protonation, which was found to be N-1 of the pyrimidine ring.

Additional Information

© 1977 American Chemical Society. Received January 19, 1977. Supported in part by the National Science Foundation and by the Public Health Service, Research Grant 11072 from the division of General Medical Science.

Additional details

Identifiers

Eprint ID
60891
Resolver ID
CaltechAUTHORS:20151008-070944702

Funding

NSF
U.S. Public Health Service (USPHS)
GM-11072

Dates

Created
2015-10-08
Created from EPrint's datestamp field
Updated
2021-11-10
Created from EPrint's last_modified field

Caltech Custom Metadata

Other Numbering System Name
Caltech Gates and Crellin Laboratories of Chemistry
Other Numbering System Identifier
5496