CaltechAUTHORS
Published May 2014 | Version public
Journal Article Metadata-only

Targeted Gene Therapy in the Treatment of X-Linked Hyper-lgM Syndrome

Creators

Abstract

X-linked hyper-IgM syndrome (XHIM) is a primary immunodeficiency with absent IgG, IgA, IgE and normal/elevated IgM due to defects in the CD40 ligand (CD40L) gene. CD40L is expressed on T-lymphocytes and is essential in the interaction between B and T cells that induces class switch recombination.

Additional Information

© 2014 Amencan Society of Gene & Cell Therapy. Session: Poster Session: Gene Targeting and Gene Correction I (5:30 PM-7:30 PM) Date/Time: Wednesday, May 21, 2014 - 5:30 PM Room: Hall A and B South

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Identifiers

Eprint ID
47322
Resolver ID
CaltechAUTHORS:20140718-100633318

Dates

Created
2014-07-18
Created from EPrint's datestamp field
Updated
2020-03-09
Created from EPrint's last_modified field